Chronic recurrent multifocal osteomyelitis in N. Greece: disease burden in pediatric patients

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Chronic recurrent multifocal osteomyelitis in N. Greece: disease burden in pediatric patients

Results Nine patients (female:8, mean age: 10 yrs) were diagnosed with CRMO. The main presenting symptoms in all patients were inflammatory pain in multiple sites, mainly in the metaphyses and epiphyses of long bones in lower limbs (mostly in proximal femur (4/9)) and swelling (7/9). 6/9 patients reported hip pain and only 1, clavicular pain. At diagnosis, fever was noted in 5/9 patients, a rai...

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Chronic Recurrent Multifocal Osteomyelitis in a 9-year-old Boy

  Chronic recurrent multifocal osteomyelitis (CRMO) is a rare aseptic, auto-inflammatory bone disorder. CRMO presents with bone pain with or without fever. The diagnosis of CRMO is a diagnosis of exclusion and should be included in the differential diagnosis of chronic inflammatory bone lesions in children. Cultures of the bone are typically sterile, antibiotic therapy does not result in clinic...

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Bone scintigraphy in diagnosing chronic recurrent multifocal osteomyelitis

A 10-year-old boy was referred to us for evaluation of FUO accompanied with bone pain in both calves. Three hours after intravenous injection of 13 mCi of 99mTc-MDP, whole body scan in multiple spot views was performed. The scan showed symmetrical areas of diffusely increased tracer uptake in multiple long bones. Histopathologic evaluation confirmed osteosclrosis and fibrotic changes...

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Chronic recurrent multifocal osteomyelitis.

Chronic recurrent multifocal osteomyelitis is an autoinflammatory disorder characterized by bone pain and fever, a course of exacerbations and remissions, and a frequent association with other inflammatory conditions. Because its etiology is largely unknown, the diagnosis is still based on clinical criteria; treatment is empiric and not always successful. The diagnosis is supported by the prese...

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Chronic recurrent multifocal osteomyelitis; manifestation, imaging and diagnosis

Chronic recurrent multifocal osteomyelitis (CRMO) is an inflammatory bone disease usually affecting children. A 9-year old boy presented with recurrent lower extremities pain and discomfort lasting for two years. In every time, symptoms vanished after several weeks. The patient received antibiotics only in one period of bone pain. In other occasions the patient didn’t received any antibiotics. ...

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ژورنال

عنوان ژورنال: Pediatric Rheumatology

سال: 2015

ISSN: 1546-0096

DOI: 10.1186/1546-0096-13-s1-p172